Identification of small molecules that inhibit the histone chaperone Asf1 and its chromatin function

The eukaryotic genome is packed into chromatin, which is important for the genomic integrity and gene regulation. Chromatin structures are maintained through assembly and disassembly of nucleosomes catalyzed by histone chaperones. Asf1 (anti-silencing function 1) is a highly conserved histone chaper...

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Detalles Bibliográficos
Autores principales: Seol, Ja-Hwan, Song, Tae-Yang, Oh, Se Eun, Jo, Chanhee, Choi, Ahreum, Kim, Byungho, Park, Jinyoung, Hong, Suji, Song, Ilrang, Jung, Kwan Young, Yang, Jae-Hyun, Park, Hwangseo, Ahn, Jin-Hyun, Han, Jeung-Whan, Cho, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Research-Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791324/
https://www.ncbi.nlm.nih.gov/pubmed/26058396
http://dx.doi.org/10.5483/BMBRep.2015.48.12.063

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