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Three-Color Chromosome Painting as Seen through the Eyes of mFISH: Another Look at Radiation-Induced Exchanges and Their Conversion to Whole-Genome Equivalency

Whole-chromosome painting (WCP) typically involves the fluorescent staining of a small number of chromosomes. Consequently, it is capable of detecting only a fraction of exchanges that occur among the full complement of chromosomes in a genome. Mathematical corrections are commonly applied to WCP da...

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Detalles Bibliográficos
Autores principales: Loucas, Bradford D., Shuryak, Igor, Cornforth, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791380/
https://www.ncbi.nlm.nih.gov/pubmed/27014627
http://dx.doi.org/10.3389/fonc.2016.00052