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Derivatization of estrogens enhances specificity and sensitivity of analysis of human plasma and serum by liquid chromatography tandem mass spectrometry
Estrogens circulate at concentrations less than 20 pg/mL in men and postmenopausal women, presenting analytical challenges. Quantitation by immunoassay is unreliable at these low concentrations. Liquid chromatography tandem mass spectrometry (LC–MS/MS) offers greater specificity and sometimes greate...
Autores principales: | Faqehi, Abdullah M.M., Cobice, Diego F., Naredo, Gregorio, Mak, Tracy C.S., Upreti, Rita, Gibb, Fraser W., Beckett, Geoffrey J., Walker, Brian R., Homer, Natalie Z.M., Andrew, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791381/ https://www.ncbi.nlm.nih.gov/pubmed/26946022 http://dx.doi.org/10.1016/j.talanta.2015.12.062 |
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