Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

Xeroderma pigmentosum (XP) is a group of genetic disorders caused by mutations of XP-associated genes, resulting in impairment of DNA repair. XP patients frequently exhibit neurological degeneration, but the underlying mechanism is unknown, in part due to lack of proper disease models. Here, we gene...

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Detalles Bibliográficos
Autores principales: Fu, Lina, Xu, Xiuling, Ren, Ruotong, Wu, Jun, Zhang, Weiqi, Yang, Jiping, Ren, Xiaoqing, Wang, Si, Zhao, Yang, Sun, Liang, Yu, Yang, Wang, Zhaoxia, Yang, Ze, Yuan, Yun, Qiao, Jie, Belmonte, Juan Carlos Izpisua, Qu, Jing, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791426/
https://www.ncbi.nlm.nih.gov/pubmed/26874523
http://dx.doi.org/10.1007/s13238-016-0244-y

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