Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice

Sister chromatid cohesion mediated by the cohesin complex is essential for chromosome segregation in mitosis and meiosis [1]. Rec8-containing cohesin, bound to Smc3/Smc1α or Smc3/Smc1β, maintains bivalent cohesion in mammalian meiosis [2, 3, 4, 5, 6]. In females, meiotic DNA replication and recombin...

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Detalles Bibliográficos
Autores principales: Burkhardt, Sabrina, Borsos, Máté, Szydlowska, Anna, Godwin, Jonathan, Williams, Suzannah A., Cohen, Paula E., Hirota, Takayuki, Saitou, Mitinori, Tachibana-Konwalski, Kikuë
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791431/
https://www.ncbi.nlm.nih.gov/pubmed/26898469
http://dx.doi.org/10.1016/j.cub.2015.12.073

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