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Continuous time Bayesian networks identify Prdm1 as a negative regulator of TH17 cell differentiation in humans

T helper 17 (TH17) cells represent a pivotal adaptive cell subset involved in multiple immune disorders in mammalian species. Deciphering the molecular interactions regulating TH17 cell differentiation is particularly critical for novel drug target discovery designed to control maladaptive inflammat...

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Detalles Bibliográficos
Autores principales:	Acerbi, Enzo, Viganò, Elena, Poidinger, Michael, Mortellaro, Alessandra, Zelante, Teresa, Stella, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791550/ https://www.ncbi.nlm.nih.gov/pubmed/26976045 http://dx.doi.org/10.1038/srep23128

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