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Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome

Genetic and epigenetic factors may predispose women to polycystic ovary syndrome (PCOS), a common heritable disorder of unclear etiology. Here we investigated differences in genome-wide gene expression and DNA methylation in adipose tissue from 64 women with PCOS and 30 controls. In total, 1720 uniq...

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Detalles Bibliográficos
Autores principales: Kokosar, Milana, Benrick, Anna, Perfilyev, Alexander, Fornes, Romina, Nilsson, Emma, Maliqueo, Manuel, Behre, Carl Johan, Sazonova, Antonina, Ohlsson, Claes, Ling, Charlotte, Stener-Victorin, Elisabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791632/
https://www.ncbi.nlm.nih.gov/pubmed/26975253
http://dx.doi.org/10.1038/srep22883

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