Targeted disruption of sp7 and myostatin with CRISPR-Cas9 results in severe bone defects and more muscular cells in common carp

The common carp (Cyprinus carpio) as one of the most important aquaculture fishes produces over 3 million metric tones annually, approximately 10% the annual production of the all farmed freshwater fish worldwide. However, the tetraploidy genome and long generation-time of the common carp have made...

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Detalles Bibliográficos
Autores principales: Zhong, Zhaomin, Niu, Pengfei, Wang, Mingyong, Huang, Guodong, Xu, Shuhao, Sun, Yi, Xu, Xiaona, Hou, Yi, Sun, Xiaowen, Yan, Yilin, Wang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791634/
https://www.ncbi.nlm.nih.gov/pubmed/26976234
http://dx.doi.org/10.1038/srep22953

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