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Adaptive engineering of a hyperthermophilic archaeon on CO and discovering the underlying mechanism by multi-omics analysis
The hyperthermophilic archaeon Thermococcus onnurineus NA1 can grow and produce H(2) on carbon monoxide (CO) and its H(2) production rates have been improved through metabolic engineering. In this study, we applied adaptive evolution to enhance H(2) productivity. After over 150 serial transfers onto...
Autores principales: | Lee, Seong Hyuk, Kim, Min-Sik, Lee, Jae-Hak, Kim, Tae Wan, Bae, Seung Seob, Lee, Sung-Mok, Jung, Hae Chang, Yang, Tae-Jun, Choi, Ae Ran, Cho, Yong-Jun, Lee, Jung-Hyun, Kwon, Kae Kyoung, Lee, Hyun Sook, Kang, Sung Gyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791640/ https://www.ncbi.nlm.nih.gov/pubmed/26975345 http://dx.doi.org/10.1038/srep22896 |
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