Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase

With the increased incidence of tuberculosis (TB) caused by Mycobacterium tuberculosis there is an urgent need for new and better anti-tubercular drugs. N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) is a key enzyme in the succinylase pathway for the biosynthesis of meso-diaminopimelic acid...

Descripción completa

Detalles Bibliográficos
Autores principales: Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A., Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791643/
https://www.ncbi.nlm.nih.gov/pubmed/26976706
http://dx.doi.org/10.1038/srep23191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791643/
https://www.ncbi.nlm.nih.gov/pubmed/26976706
http://dx.doi.org/10.1038/srep23191

Ejemplares similares