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Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys

BACKGROUND: The production of properly folded, recombinant sub-unit Plasmodium falciparum malaria vaccine candidates in sufficient quantities is often a challenge. Success in vaccine immunogenicity studies in small animal models does not always predict immunogenicity in non-human primates and/or hum...

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Detalles Bibliográficos
Autores principales: Burns, James M., Miura, Kazutoyo, Sullivan, JoAnn, Long, Carole A., Barnwell, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791798/
https://www.ncbi.nlm.nih.gov/pubmed/26975721
http://dx.doi.org/10.1186/s12936-016-1226-5