Cargando…

Longitudinal Transcriptome Analysis Reveals a Sustained Differential Gene Expression Signature in Patients Treated for Acute Lyme Disease

Lyme disease is a tick-borne illness caused by the bacterium Borrelia burgdorferi, and approximately 10 to 20% of patients report persistent symptoms lasting months to years despite appropriate treatment with antibiotics. To gain insights into the molecular basis of acute Lyme disease and the ensuin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bouquet, Jerome, Soloski, Mark J., Swei, Andrea, Cheadle, Chris, Federman, Scot, Billaud, Jean-Noel, Rebman, Alison W., Kabre, Beniwende, Halpert, Richard, Boorgula, Meher, Aucott, John N., Chiu, Charles Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791844/ https://www.ncbi.nlm.nih.gov/pubmed/26873097 http://dx.doi.org/10.1128/mBio.00100-16

Ejemplares similares

A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients
por: Morrissette, Madeleine, et al.
Publicado: (2020)

A diagnostic classifier for gene expression-based identification of early Lyme disease
por: Servellita, Venice, et al.
Publicado: (2022)

Post-treatment Lyme Disease as a Model for Persistent Symptoms in Lyme Disease
por: Rebman, Alison W., et al.
Publicado: (2020)

Gene set predictor for post-treatment Lyme disease
por: Clarke, Daniel J.B., et al.
Publicado: (2022)

The Clinical, Symptom, and Quality-of-Life Characterization of a Well-Defined Group of Patients with Posttreatment Lyme Disease Syndrome
por: Rebman, Alison W., et al.
Publicado: (2017)

886. Impact of Race on the Early Diagnosis and Treatment of Lyme Disease
por: Starke, Samuel J, et al.
Publicado: (2023)

Probable late lyme disease: a variant manifestation of untreated Borrelia burgdorferi infection
por: Aucott, John N, et al.
Publicado: (2012)

Lyme Disease with Erythema Migrans and Seventh Nerve Palsy in an African-American Man
por: Dennison, Rebekah, et al.
Publicado: (2019)

Symptom heterogeneity and patient subgroup classification among US patients with post-treatment Lyme disease: an observational study
por: Rebman, Alison W, et al.
Publicado: (2021)

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease
por: Blum, Lisa K., et al.
Publicado: (2018)

Contrast Sensitivity Loss in Patients With Posttreatment Lyme Disease
por: Rebman, Alison W., et al.
Publicado: (2021)

Post-treatment Lyme disease syndrome symptomatology and the impact on life functioning: is there something here?
por: Aucott, John N., et al.
Publicado: (2012)

Peptidylarginine Deiminase 2 Autoantibodies Are Linked to Less Severe Disease in Multiple Sclerosis and Post-treatment Lyme Disease
por: Kim, Yaewon, et al.
Publicado: (2022)

Direct Molecular Detection and Genotyping of Borrelia burgdorferi from Whole Blood of Patients with Early Lyme Disease
por: Eshoo, Mark W., et al.
Publicado: (2012)

LB17. Immunosequencing of the T-Cell Receptor Repertoire Reveals Signatures Specific for Diagnosis and Characterization of Early Lyme Disease
por: Dalai, Sudeb C, et al.
Publicado: (2021)

Obstacles to diagnosis and treatment of Lyme disease in the USA: a qualitative study
por: Hirsch, Annemarie G, et al.
Publicado: (2018)

Utility of Metagenomic Next-Generation Sequencing for Characterization of HIV and Human Pegivirus Diversity
por: Luk, Ka-Cheung, et al.
Publicado: (2015)

Serum Inflammatory Mediators as Markers of Human Lyme Disease Activity
por: Soloski, Mark J., et al.
Publicado: (2014)

Predicting Lyme Disease From Patients' Peripheral Blood Mononuclear Cells Profiled With RNA-Sequencing
por: Clarke, Daniel J. B., et al.
Publicado: (2021)

The Lyme and Tickborne Disease Dashboard: A map-based resource to promote public health awareness and research collaboration
por: Curriero, Frank C., et al.
Publicado: (2021)

Outpatient visits before and after Lyme disease diagnosis in a Maryland employer-based health plan
por: Rebman, Alison W., et al.
Publicado: (2023)

The Genome Sequence of Lone Star Virus, a Highly Divergent Bunyavirus Found in the Amblyomma americanum Tick
por: Swei, Andrea, et al.
Publicado: (2013)

Risk Factors and Outcomes of Treatment Delays in Lyme Disease: A Population-Based Retrospective Cohort Study
por: Hirsch, Annemarie G., et al.
Publicado: (2020)

The General Symptom Questionnaire-30 (GSQ-30): A Brief Measure of Multi-System Symptom Burden in Lyme Disease
por: Fallon, Brian A., et al.
Publicado: (2019)

Early Disseminated Lyme Disease with Carditis Complicated by Posttreatment Lyme Disease Syndrome
por: Novak, Cheryl, et al.
Publicado: (2017)

Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [(11)C]DPA-713 PET
por: Coughlin, Jennifer M., et al.
Publicado: (2018)

Long-haul COVID: heed the lessons from other infection-triggered illnesses
por: Aucott, John N, et al.
Publicado: (2021)

A multimodal neuroimaging study of brain abnormalities and clinical correlates in post treatment Lyme disease
por: Marvel, Cherie L., et al.
Publicado: (2022)

Recent Progress in Lyme Disease and Remaining Challenges
por: Bobe, Jason R., et al.
Publicado: (2021)

Misdiagnosis of early Lyme disease as the summer flu
por: Aucott, John N., et al.
Publicado: (2011)

Comparative vector competence of North American Lyme disease vectors
por: Couper, Lisa I., et al.
Publicado: (2020)

Diagnostic challenges of early Lyme disease: Lessons from a community case series
por: Aucott, John, et al.
Publicado: (2009)

Drivers and patterns of microbial community assembly in a Lyme disease vector
por: Couper, Lisa I., et al.
Publicado: (2019)

Lyme Disease in the Era of COVID-19: A Delayed Diagnosis and Risk for Complications
por: Novak, Cheryl B., et al.
Publicado: (2021)

Health Care Costs, Utilization and Patterns of Care following Lyme Disease
por: Adrion, Emily R., et al.
Publicado: (2015)

Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen
por: Bouquet, Jerome, et al.
Publicado: (2017)

Effects of an invasive forest pathogen on abundance of ticks and their vertebrate hosts in a California Lyme disease focus
por: Swei, Andrea, et al.
Publicado: (2010)

Atypical Erythema Migrans in Patients with PCR-Positive Lyme Disease
por: Schutzer, Steven E., et al.
Publicado: (2013)

Bull's-Eye and Nontarget Skin Lesions of Lyme Disease: An Internet Survey of Identification of Erythema Migrans
por: Aucott, John N., et al.
Publicado: (2012)

RNA-Seq Analysis of Gene Expression, Viral Pathogen, and B-Cell/T-Cell Receptor Signatures in Complex Chronic Disease
por: Bouquet, Jerome, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s5ricf9v430fsovn8pb0p6tj39