The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility

Ergosterol is a major and specific component of the fungal plasma membrane, and thus, the cytochrome P450 enzymes (Erg proteins) that catalyze ergosterol synthesis have been selected as valuable targets of azole antifungals. However, the opportunistic pathogen Aspergillus fumigatus has developed wor...

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Detalles Bibliográficos
Autores principales: Song, Jinxing, Zhai, Pengfei, Zhang, Yuanwei, Zhang, Caiyun, Sang, Hong, Han, Guanzhu, Keller, Nancy P., Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791848/
https://www.ncbi.nlm.nih.gov/pubmed/26908577
http://dx.doi.org/10.1128/mBio.01919-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791848/
https://www.ncbi.nlm.nih.gov/pubmed/26908577
http://dx.doi.org/10.1128/mBio.01919-15

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