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Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

Immunoassays are currently needed to quantify Loa loa microfilariae (mf). To address this need, we have conducted proteomic and bioinformatic analyses of proteins present in the urine of a Loa mf-infected patient and used this information to identify putative biomarkers produced by L. loa mf. In tot...

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Detalles Bibliográficos
Autores principales: Drame, Papa M., Meng, Zhaojing, Bennuru, Sasisekhar, Herrick, Jesica A., Veenstra, Timothy D., Nutman, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791851/
https://www.ncbi.nlm.nih.gov/pubmed/26884435
http://dx.doi.org/10.1128/mBio.02132-15