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Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

BACKGROUND: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins in various signaling pathways, miR-21 is an attractive target for genetic and...

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Detalles Bibliográficos
Autores principales: Peralta-Zaragoza, Oscar, Deas, Jessica, Meneses-Acosta, Angélica, De la O-Gómez, Faustino, Fernández-Tilapa, Gloria, Gómez-Cerón, Claudia, Benítez-Boijseauneau, Odelia, Burguete-García, Ana, Torres-Poveda, Kirvis, Bermúdez-Morales, Victor Hugo, Madrid-Marina, Vicente, Rodríguez-Dorantes, Mauricio, Hidalgo-Miranda, Alfredo, Pérez-Plasencia, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791868/
https://www.ncbi.nlm.nih.gov/pubmed/26975392
http://dx.doi.org/10.1186/s12885-016-2231-3