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Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential

BACKGROUND: The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life. DNA methylation is an epigenetic mechanism which plays a crucial role in development and gene expression regulation. Under investig...

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Detalles Bibliográficos
Autores principales: Górnikiewicz, Bartosz, Ronowicz, Anna, Krzemiński, Michał, Sachadyn, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791959/
https://www.ncbi.nlm.nih.gov/pubmed/26979619
http://dx.doi.org/10.1186/s12864-016-2545-1