Cargando…
Protective Mechanisms of Thymoquinone on Methotrexate-induced Intestinal Toxicity in Rats
BACKGROUND: Intestinal toxicity is a serious side effect in methotrexate (MTX) chemotherapy. OBJECTIVE: To investigate the mechanisms by which the anticancer drug MTX-induced intestinal damage could be prevented by thymoquinone (TQ), an active ingredient of Nigella sativa. MATERIALS AND METHODS: TQ...
Autores principales: | El-Sheikh, Azza A., Morsy, Mohamed A., Hamouda, Azza H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792005/ https://www.ncbi.nlm.nih.gov/pubmed/27041864 http://dx.doi.org/10.4103/0973-1296.176106 |
Ejemplares similares
-
Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats
por: El-Sheikh, Azza A. K., et al.
Publicado: (2015) -
Mechanism of testicular protection of carvedilol in streptozotocin-induced diabetic rats
por: Ramzy, Maggie M., et al.
Publicado: (2014) -
Paeonol Protects Against Methotrexate-Induced Nephrotoxicity via Upregulation of P-gp Expression and Inhibition of TLR4/NF-κB Pathway
por: Morsy, Mohamed A., et al.
Publicado: (2022) -
Modulation of Liver P-Glycoprotien Expression May Contribute to Gossypin Protection against Methotrexate-Induced Hepatotoxicity
por: Mohamed, Mervat, et al.
Publicado: (2021) -
Evaluation of the Protective Effect of Citral, Silymarin, and Thymoquinone on Methotrexate-Induced Lung Injury in Rats
por: Sakineh, Amani, et al.
Publicado: (2023)