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Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog

We have recently shown that a combination of microRNAs, miR combo, can directly reprogram cardiac fibroblasts into functional cardiomyocytes in vitro and in vivo. However, direct reprogramming strategies are inefficient and slow. Moving towards the eventual goal of clinical application it is necessa...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowen, Hodgkinson, Conrad P, Lu, Kefeng, Payne, Alan J, Pratt, Richard E, Dzau, Victor J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792153/
https://www.ncbi.nlm.nih.gov/pubmed/26975336
http://dx.doi.org/10.1038/srep23017