Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights

MICALs (Molecule Interacting with CasL) are conserved multidomain enzymes essential for cytoskeletal reorganization in nerve development, endocytosis, and apoptosis. In these enzymes, a type-2 calponin homology (CH) domain always follows an N-terminal monooxygenase (MO) domain. Although the CH domai...

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Detalles Bibliográficos
Autores principales: Alqassim, Saif S., Urquiza, Mauricio, Borgnia, Eitan, Nagib, Marc, Amzel, L. Mario, Bianchet, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792234/
https://www.ncbi.nlm.nih.gov/pubmed/26935886
http://dx.doi.org/10.1038/srep22176

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