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Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes
Keratinocytes are the first cells that come into direct contact with external tactile stimuli; however, their role in touch transduction in vivo is not clear. The ion channel Transient Receptor Potential Ankyrin 1 (TRPA1) is essential for some mechanically-gated currents in sensory neurons, amplifie...
Autores principales: | Zappia, Katherine J., Garrison, Sheldon R., Palygin, Oleg, Weyer, Andy D., Barabas, Marie E., Lawlor, Michael W., Staruschenko, Alexander, Stucky, Cheryl L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792390/ https://www.ncbi.nlm.nih.gov/pubmed/26978657 http://dx.doi.org/10.1371/journal.pone.0151602 |
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