Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in erk-responsive lung cancer

Metastatic spread of cancer cells portends a poor prognosis and mortality for lung cancer patients. Hypoxia-inducible factor-1α (HIF-1α) enhances tumor cell motility by activating the epithelial-to-mesenchymal transition (EMT), which is considered a prerequisite for metastasis. Recent studies of mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Chun-Wen, Chen, Po-Ming, Hsieh, Yi-Hsien, Weng, Chung-Chih, Chang, Chia-Wei, Yao, Chung-Chin, Hu, Ling-Yueh, Wu, Pei-Ei, Shen, Chen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792553/
https://www.ncbi.nlm.nih.gov/pubmed/26528854

Ejemplares similares

Ejemplares similares