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Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer

The underlying mechanisms for acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in about 30%-40% of non-small cell lung cancer (NSCLC) patients remain elusive. Recent studies have suggested that activation of epithelial-mesenchymal transition (EMT) and ty...

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Detalles Bibliográficos
Autores principales:	Zhou, Juan, Wang, Jinjing, Zeng, Yunyun, Zhang, Xi, Hu, Qiaoting, Zheng, Jihua, Chen, Bei, Xie, Bo, Zhang, Wei-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792560/ https://www.ncbi.nlm.nih.gov/pubmed/26554308

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