Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation

CD44 is a widely known cancer stem cells marker in various cancers and validated to function in tumor growth, survival and tumor metastasis. In this study, we first established C3A-derived liver cancer stem cells by OSKM method [OCT4, SOX2, KLF4, and c-MYC], termed C3A-induced cancer stem cells (C3A...

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Detalles Bibliográficos
Autores principales: Han, Shuo, Guo, Jinhai, Liu, Yinan, Zhang, Zhi, He, Qihua, Li, Peng, Zhang, Mingzhi, Sun, Haojie, Li, Ruizhi, Li, Yang, Zeng, Wotan, Liu, Jinwen, Lian, Lejian, Gao, Yi, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792568/
https://www.ncbi.nlm.nih.gov/pubmed/26540347

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