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PPARα induces cell apoptosis by destructing Bcl2

PPARα belongs to the peroxisome-proliferator-activated receptors (PPARs) family, which plays a critical role in inhibiting cell proliferation and tumorigenesis, while the molecular mechanism is still unclear. Here we report that PPARα serves as an E3 ubiquitin ligase to govern Bcl2 protein stability...

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Detalles Bibliográficos
Autores principales:	Gao, Jiaming, Liu, Qian, Xu, Ying, Gong, Xin, Zhang, Runyun, Zhou, Chenglin, Su, Zhaoliang, Jin, Jianhua, Shi, Haifeng, Shi, Juanjuan, Hou, Yongzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792581/ https://www.ncbi.nlm.nih.gov/pubmed/26556865

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