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Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma
The intracytoplasmic tyrosine kinase Src serves both as a conduit and a regulator for multiple processes required for the proliferation and survival cancer cells. In some cancers, Src engages with receptor tyrosine kinases to mediate downstream signaling and in other cancers, it regulates gene expre...
Autores principales: | Lue, Hui-Wen, Cole, Brook, Rao, Soumya A. M., Podolak, Jennifer, Van Gaest, Ahna, King, Carly, Eide, Christopher A., Wilmot, Beth, Xue, Changhui, Spellman, Paul T., Heiser, Laura M., Tyner, Jeffrey W., Thomas, George V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792584/ https://www.ncbi.nlm.nih.gov/pubmed/26625308 |
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