Cargando…

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer

Male breast cancer comprises less than 1% of breast cancer diagnoses. Although estrogen exposure has been causally linked to the development of female breast cancers, the etiology of male breast cancer is unclear. Here, we show via fluorescence in situ hybridization (FISH) and droplet digital PCR (d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, Hong Yuen, Wang, Grace M., Croessmann, Sarah, Zabransky, Daniel J., Chu, David, Garay, Joseph P., Cidado, Justin, Cochran, Rory L., Beaver, Julia A., Aggarwal, Anita, Liu, Min-Ling, Argani, Pedram, Meeker, Alan, Hurley, Paula J., Lauring, Josh, Park, Ben Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792601/ https://www.ncbi.nlm.nih.gov/pubmed/26702755

Ejemplares similares

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes
por: Cochran, Rory L., et al.
Publicado: (2015)

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation
por: Cidado, Justin, et al.
Publicado: (2016)

Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway
por: Inoue, Miki, et al.
Publicado: (2022)

TMSB4 Overexpression Enhances the Potency of Marrow Mesenchymal Stromal Cells for Myocardial Repair
por: Tang, Shiyuan, et al.
Publicado: (2021)

TMSB10 acts as a biomarker and promotes progression of clear cell renal cell carcinoma
por: Pan, Qiufeng, et al.
Publicado: (2020)

TMSB4X: A novel prognostic marker for non-small cell lung cancer
por: Yang, Ze, et al.
Publicado: (2023)

Needles in a haystack: finding recurrent genomic changes in breast cancer
por: Cidado, Justin, et al.
Publicado: (2012)

Thymosin beta 15A (TMSB15A) is a predictor of chemotherapy response in triple-negative breast cancer
por: Darb-Esfahani, S, et al.
Publicado: (2012)

The TMSB4 Pseudogene LncRNA Functions as a Competing Endogenous RNA to Promote Cartilage Degradation in Human Osteoarthritis
por: Liu, Qiang, et al.
Publicado: (2016)

Pancancer landscape analysis of the thymosin family identified TMSB10 as a potential prognostic biomarker and immunotherapy target in glioma
por: Xiong, Ye, et al.
Publicado: (2022)

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model
por: Cravero, Karen, et al.
Publicado: (2022)

Changes in Biomechanical Properties of A375 Cells Due to the Silencing of TMSB4X Expression Are Not Directly Correlated with Alterations in Their Stemness Features
por: Makowiecka, Aleksandra, et al.
Publicado: (2021)

Proteomic characterisation of prostate cancer intercellular communication reveals cell type-selective signalling and TMSB4X-dependent fibroblast reprogramming
por: Wu, Yunjian, et al.
Publicado: (2022)

Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma
por: Tantawy, Marwa, et al.
Publicado: (2023)

DNMT1 maintains the methylation of miR‐152‐3p to regulate TMSB10 expression, thereby affecting the biological characteristics of colorectal cancer cells
por: Wang, Chenchen, et al.
Publicado: (2020)

The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation
por: Garay, Joseph P, et al.
Publicado: (2012)

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11
por: Lafage-Pochitaloff, Marina, et al.
Publicado: (2022)

Evidence for two candidate tumour suppressor loci on chromosome 9q in transitional cell carcinoma (TCC) of the bladder but no homozygous deletions in bladder tumour cell lines
por: Tilborg, A A G van, et al.
Publicado: (1999)

A fertile male with a single sY86 deletion on the Y chromosome
por: Jia, Yin, et al.
Publicado: (2019)

Divergent effects of peripheral and global neuropeptide Y deletion
por: Wee, Natalie K.Y., et al.
Publicado: (2020)

Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity
por: Yi, Kyung H., et al.
Publicado: (2015)

Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma
por: Chen, Juan, et al.
Publicado: (2012)

Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma
por: Aksoy Yasar, Fatma Betul, et al.
Publicado: (2022)

Exclusion of BBC1 and CMAR as candidate breast tumour-suppressor genes.
por: Moerland, E., et al.
Publicado: (1997)

Identification of LZAP as a New Candidate Tumor Suppressor in Hepatocellular Carcinoma
por: Zhao, Jing-jing, et al.
Publicado: (2011)

TWIST2: A new candidate tumor suppressor in prostate cancer
por: Zhao, Chengxiao, et al.
Publicado: (2019)

Targeted Deletion of Neuropeptide Y (NPY) Modulates Experimental Colitis
por: Chandrasekharan, Bindu, et al.
Publicado: (2008)

Deletions in the Y-derived amelogenin gene fragment in the Indian population
por: Kashyap, VK, et al.
Publicado: (2006)

Mice With Partial Deletion of Y-Heterochromatin Exhibits Stress Vulnerability
por: Dey, Sandeep Kumar, et al.
Publicado: (2018)

Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies
por: Tanaka, Tomoyuki, et al.
Publicado: (2017)

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
por: Cheng, Jiqiu, et al.
Publicado: (2017)

Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development
por: Weren, Robbert DA, et al.
Publicado: (2015)

Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration
por: Schulz, Alexander, et al.
Publicado: (2016)

Probabilidad y estadística III : inferencia estadística
por: Hurley Phee, Dennis
Publicado: (1984)

Cathepsin K: A Novel Diagnostic and Predictive Biomarker for Renal Tumors
por: Caliò, Anna, et al.
Publicado: (2021)

Expression analysis of candidate breast tumour suppressor genes on chromosome 16q
por: van Wezel, Tom, et al.
Publicado: (2005)

Identification of Candidate Tumour Suppressor Genes Frequently Methylated in Renal Cell Carcinoma
por: Morris, Mark R., et al.
Publicado: (2010)

Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion
por: Li, Wei, et al.
Publicado: (2010)

Sprouty1 is a candidate tumor suppressor gene in medullary thyroid carcinoma
por: Macià, Anna, et al.
Publicado: (2011)

AB122. The structure and function of NKAIN2—a candidate tumor suppressor
por: Zhao, Shanchao, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_c30bpfb4sq3bdnl0fhd4gkf75c