G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression

The euchromatin histone methyltransferase 2 (also known as G9a) methylates histone H3K9 to repress gene expression, but it also acts as a coactivator for some nuclear receptors. The molecular mechanisms underlying this activation remain elusive. Here we show that G9a functions as a coactivator of th...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Peng, Danni, Xi, Yuanxin, Yuan, Chao, Sagum, Cari A., Klein, Brianna J., Tanaka, Kaori, Wen, Hong, Kutateladze, Tatiana G., Li, Wei, Bedford, Mark T., Shi, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792926/
https://www.ncbi.nlm.nih.gov/pubmed/26960573
http://dx.doi.org/10.1038/ncomms10810

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