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IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease
The ability of CD4+ T cells to change their phenotype and to specialize into different functional subsets may enhance the risk of autoimmune diseases. Here we investigate how a pleiotropic cytokine interleukin (IL)-15 may modify the functional commitment of CD4+ T cells expressing the lineage-associ...
Autores principales: | Tosiek, Milena J., Fiette, Laurence, El Daker, Sary, Eberl, Gérard, Freitas, Antonio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792960/ https://www.ncbi.nlm.nih.gov/pubmed/26964669 http://dx.doi.org/10.1038/ncomms10888 |
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