IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

Dysregulated inflammasome activation contributes to respiratory infections and pathologic airway inflammation. Through basic and translational approaches involving murine models and human genetic epidemiology, we show here the importance of the different inflammasomes in regulating inflammatory resp...

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Detalles Bibliográficos
Autores principales: Iannitti, Rossana G., Napolioni, Valerio, Oikonomou, Vasilis, De Luca, Antonella, Galosi, Claudia, Pariano, Marilena, Massi-Benedetti, Cristina, Borghi, Monica, Puccetti, Matteo, Lucidi, Vincenzina, Colombo, Carla, Fiscarelli, Ersilia, Lass-Flörl, Cornelia, Majo, Fabio, Cariani, Lisa, Russo, Maria, Porcaro, Luigi, Ricciotti, Gabriella, Ellemunter, Helmut, Ratclif, Luigi, De Benedictis, Fernando Maria, Talesa, Vincenzo Nicola, Dinarello, Charles A., van de Veerdonk, Frank L., Romani, Luigina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793079/
https://www.ncbi.nlm.nih.gov/pubmed/26972847
http://dx.doi.org/10.1038/ncomms10791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793079/
https://www.ncbi.nlm.nih.gov/pubmed/26972847
http://dx.doi.org/10.1038/ncomms10791

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