Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1

Sister chromatid cohesion is mediated by cohesin, whose Smc1, Smc3, and kleisin (Scc1) subunits form a ring structure that entraps sister DNAs. The ring is opened either by separase, which cleaves Scc1 during anaphase, or by a releasing activity involving Wapl, Scc3, and Pds5, which bind to Scc1 and...

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Detalles Bibliográficos
Autores principales: Lee, Byung-Gil, Roig, Maurici B., Jansma, Marijke, Petela, Naomi, Metson, Jean, Nasmyth, Kim, Löwe, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793087/
https://www.ncbi.nlm.nih.gov/pubmed/26923598
http://dx.doi.org/10.1016/j.celrep.2016.02.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793087/
https://www.ncbi.nlm.nih.gov/pubmed/26923598
http://dx.doi.org/10.1016/j.celrep.2016.02.020

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