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P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats

Blockading P2X7 receptor(P2X7R) provides neuroprotection toward various neurological disorders, including stroke, traumatic brain injury, and subarachnoid hemorrhage. However, whether and how P2X7 receptor suppression protects blood-brain barrier(BBB) after intracerebral hemorrhage(ICH) remains unex...

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Detalles Bibliográficos
Autores principales: Zhao, Hengli, Zhang, Xuan, Dai, Zhiqiang, Feng, Yang, Li, Qiang, Zhang, John H., Liu, Xin, Chen, Yujie, Feng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793194/
https://www.ncbi.nlm.nih.gov/pubmed/26980524
http://dx.doi.org/10.1038/srep23286