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P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats
Blockading P2X7 receptor(P2X7R) provides neuroprotection toward various neurological disorders, including stroke, traumatic brain injury, and subarachnoid hemorrhage. However, whether and how P2X7 receptor suppression protects blood-brain barrier(BBB) after intracerebral hemorrhage(ICH) remains unex...
Autores principales: | Zhao, Hengli, Zhang, Xuan, Dai, Zhiqiang, Feng, Yang, Li, Qiang, Zhang, John H., Liu, Xin, Chen, Yujie, Feng, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793194/ https://www.ncbi.nlm.nih.gov/pubmed/26980524 http://dx.doi.org/10.1038/srep23286 |
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