Cargando…
Insights into the mechanisms of RNA secondary structure destabilization by the HIV-1 nucleocapsid protein
The mature HIV-1 nucleocapsid protein NCp7 (NC) plays a key role in reverse transcription facilitating the two obligatory strand transfers. Several properties contribute to its efficient chaperon activity: preferential binding to single-stranded regions, nucleic acid aggregation, helix destabilizati...
Autores principales: | Belfetmi, Anissa, Zargarian, Loussiné, Tisné, Carine, Sleiman, Dona, Morellet, Nelly, Lescop, Ewen, Maskri, Ouerdia, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793207/ https://www.ncbi.nlm.nih.gov/pubmed/26826129 http://dx.doi.org/10.1261/rna.054445.115 |
Ejemplares similares
-
Investigation of the Low-Populated Excited States of the HIV-1 Nucleocapsid Domain
por: Mouhand, Assia, et al.
Publicado: (2022) -
Dynamics of Linker Residues Modulate the Nucleic Acid Binding Properties of the HIV-1 Nucleocapsid Protein Zinc Fingers
por: Zargarian, Loussiné, et al.
Publicado: (2014) -
Overview of the Nucleic-Acid Binding Properties of the HIV-1 Nucleocapsid Protein in Its Different Maturation States
por: Mouhand, Assia, et al.
Publicado: (2020) -
Intrinsic Nucleic Acid Dynamics Modulates HIV-1 Nucleocapsid Protein Binding to Its Targets
por: Bazzi, Ali, et al.
Publicado: (2012) -
Modulation of the HIV nucleocapsid dynamics finely tunes its RNA-binding properties during virion genesis
por: Mouhand, Assia, et al.
Publicado: (2018)