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Low Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms
BACKGROUND: New sequencing technologies have enabled the identification of mutations in Ten-eleven-translocation 2 (TET2), an enzyme that catalyzes the conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5-hmC) in myeloid neoplasms. We have recently identified reduced TET2 mRNA expression i...
Autores principales: | Scopim-Ribeiro, Renata, Machado-Neto, João Agostinho, de Melo Campos, Paula, Niemann, Fernanda Soares, Lorand-Metze, Irene, Costa, Fernando Ferreira, Olalla Saad, Sara Teresinha, Traina, Fabiola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793581/ https://www.ncbi.nlm.nih.gov/pubmed/26984174 http://dx.doi.org/10.1186/s13000-016-0476-4 |
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