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Development of new fusion proteins for visualizing amyloid-β oligomers in vivo

The intracellular accumulation of amyloid-β (Aβ) oligomers critically contributes to disease progression in Alzheimer’s disease (AD) and can be the potential target of AD therapy. Direct observation of molecular dynamics of Aβ oligomers in vivo is key for drug discovery research, however, it has bee...

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Detalles Bibliográficos
Autores principales:	Ochiishi, Tomoyo, Doi, Motomichi, Yamasaki, Kazuhiko, Hirose, Keiko, Kitamura, Akira, Urabe, Takao, Hattori, Nobutaka, Kinjo, Masataka, Ebihara, Tatsuhiko, Shimura, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793674/ https://www.ncbi.nlm.nih.gov/pubmed/26982553 http://dx.doi.org/10.1038/srep22712

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