Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4

BACKGROUND: Adenylate kinase is a key enzyme in the high-energy phosphoryl transfer reaction in living cells. An isoform of this enzyme, adenylate kinase 4 (AK4), is localized in the mitochondrial matrix and is believed to be involved in stress, drug resistance, malignant transformation in cancer, a...

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Detalles Bibliográficos
Autores principales: Fujisawa, Koichi, Terai, Shuji, Takami, Taro, Yamamoto, Naoki, Yamasaki, Takahiro, Matsumoto, Toshihiko, Yamaguchi, Kazuhito, Owada, Yuji, Nishina, Hiroshi, Noma, Takafumi, Sakaida, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793738/
https://www.ncbi.nlm.nih.gov/pubmed/26980435
http://dx.doi.org/10.1186/s13046-016-0322-2

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