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Elucidating the genotype–phenotype map by automatic enumeration and analysis of the phenotypic repertoire

BACKGROUND: The gap between genotype and phenotype is filled by complex biochemical systems most of which are poorly understood. Because these systems are complex, it is widely appreciated that quantitative understanding can only be achieved with the aid of mathematical models. However, formulating...

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Detalles Bibliográficos
Autores principales: Lomnitz, Jason G, Savageau, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794114/
https://www.ncbi.nlm.nih.gov/pubmed/26998346
http://dx.doi.org/10.1038/npjsba.2015.3