CD117(+) Dendritic and Mast Cells Are Dependent on RasGRP4 to Function as Accessory Cells for Optimal Natural Killer Cell-Mediated Responses to Lipopolysaccharide

Ras guanine nucleotide-releasing protein-4 (RasGRP4) is an evolutionarily conserved calcium-regulated, guanine nucleotide exchange factor and diacylglycerol/phorbol ester receptor. While an important intracellular signaling protein for CD117(+) mast cells (MCs), its roles in other immune cells is le...

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Detalles Bibliográficos
Autores principales: Zhou, Saijun, Tanaka, Kumiko, O’Keeffe, Meredith, Qi, Miao, El-Assaad, Fatima, Weaver, James C., Chen, Gang, Weatherall, Christopher, Wang, Ying, Giannakopoulos, Bill, Chen, Liming, Yu, DeMint, Hamilton, Matthew J., Wensing, Lislaine A., Stevens, Richard L., Krilis, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794117/
https://www.ncbi.nlm.nih.gov/pubmed/26982501
http://dx.doi.org/10.1371/journal.pone.0151638

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