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Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination

Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activity. Two modifications to the IgG constant domain (...

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Detalles Bibliográficos
Autores principales: Mahan, Alison E., Jennewein, Madeleine F., Suscovich, Todd, Dionne, Kendall, Tedesco, Jacquelynne, Chung, Amy W., Streeck, Hendrik, Pau, Maria, Schuitemaker, Hanneke, Francis, Don, Fast, Patricia, Laufer, Dagna, Walker, Bruce D., Baden, Lindsey, Barouch, Dan H., Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794126/
https://www.ncbi.nlm.nih.gov/pubmed/26982805
http://dx.doi.org/10.1371/journal.ppat.1005456