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Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activity. Two modifications to the IgG constant domain (...
Autores principales: | Mahan, Alison E., Jennewein, Madeleine F., Suscovich, Todd, Dionne, Kendall, Tedesco, Jacquelynne, Chung, Amy W., Streeck, Hendrik, Pau, Maria, Schuitemaker, Hanneke, Francis, Don, Fast, Patricia, Laufer, Dagna, Walker, Bruce D., Baden, Lindsey, Barouch, Dan H., Alter, Galit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794126/ https://www.ncbi.nlm.nih.gov/pubmed/26982805 http://dx.doi.org/10.1371/journal.ppat.1005456 |
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