Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis

Rare mutations in PROC, PROS1 or SERPINC1 as well as common variants in F5, F2, F11 and SERPINC1 have been identified as risk factors for deep vein thrombosis (DVT). To identify novel genetic risk factors for DVT, we have developed and applied next-generation DNA sequencing (NGS) of the coding area...

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Detalles Bibliográficos
Autores principales: Gorski, Marcin M., Lotta, Luca A., Pappalardo, Emanuela, de Haan, Hugoline G., Passamonti, Serena M., van Hylckama Vlieg, Astrid, Martinelli, Ida, Peyvandi, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794167/
https://www.ncbi.nlm.nih.gov/pubmed/26982741
http://dx.doi.org/10.1371/journal.pone.0151347

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