Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution

Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declining Foxn1 expression with age results in stereotypic...

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Detalles Bibliográficos
Autores principales: O’Neill, Kathy E., Bredenkamp, Nicholas, Tischner, Christin, Vaidya, Harsh J., Stenhouse, Frances H., Peddie, C. Diana, Nowell, Craig S., Gaskell, Terri, Blackburn, C. Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794177/
https://www.ncbi.nlm.nih.gov/pubmed/26983083
http://dx.doi.org/10.1371/journal.pone.0151666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794177/
https://www.ncbi.nlm.nih.gov/pubmed/26983083
http://dx.doi.org/10.1371/journal.pone.0151666

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