Cargando…
Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support
The factors defining the correct folding and stability of integral membrane proteins are poorly understood. Folding of only a few select membrane proteins has been scrutinised, leaving considerable deficiencies in knowledge for large protein families, such as G protein coupled receptors (GPCRs). Com...
Autores principales: | Di Bartolo, Natalie, Compton, Emma L. R., Warne, Tony, Edwards, Patricia C., Tate, Christopher G., Schertler, Gebhard F. X., Booth, Paula J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794186/ https://www.ncbi.nlm.nih.gov/pubmed/26982879 http://dx.doi.org/10.1371/journal.pone.0151582 |
Ejemplares similares
-
The 2.1 Å Resolution Structure of Cyanopindolol-Bound β(1)-Adrenoceptor Identifies an Intramembrane Na(+) Ion that Stabilises the Ligand-Free Receptor
por: Miller-Gallacher, Jennifer L., et al.
Publicado: (2014) -
The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor
por: Warne, Tony, et al.
Publicado: (2011) -
High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs
por: Wu, Na, et al.
Publicado: (2021) -
Efficient production of a functional G protein-coupled receptor in E. coli for structural studies
por: Abiko, Layara Akemi, et al.
Publicado: (2021) -
A complete picture of protein unfolding and refolding in surfactants
por: Pedersen, Jannik Nedergaard, et al.
Publicado: (2019)