Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice

Mutation of DJ-1 (PARK7) has been linked to the development of early-onset Parkinson’s disease (PD). However, the underlying molecular mechanism is still unclear. This study is aimed to compare the sensitivity of nigrostriatal dopaminergic neurons to lipopolysaccharide (LPS) challenge between DJ-1 k...

Descripción completa

Detalles Bibliográficos
Autores principales: Chien, Chia-Hung, Lee, Ming-Jen, Liou, Houng-Chi, Liou, Horng-Huei, Fu, Wen-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794203/
https://www.ncbi.nlm.nih.gov/pubmed/26982707
http://dx.doi.org/10.1371/journal.pone.0151569

Ejemplares similares

Ejemplares similares