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Modified Newcastle disease virus vectors expressing the H5 hemagglutinin induce enhanced protection against highly pathogenic H5N1 avian influenza virus in chickens

Naturally-occurring attenuated strains of Newcastle disease virus (NDV) are being developed as vaccine vectors for use in poultry and humans. However, some NDV strains, such as Beaudette C (BC), may retain too much virulence in poultry for safe use, and more highly attenuated strains may be suboptim...

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Detalles Bibliográficos
Autores principales:	Kim, Shin-Hee, Paldurai, Anandan, Xiao, Sa, Collins, Peter L., Samal, Siba K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. Published by Elsevier Ltd. 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794254/ https://www.ncbi.nlm.nih.gov/pubmed/24968158 http://dx.doi.org/10.1016/j.vaccine.2014.06.061

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