Bone marrow transplantation alters lung antigen presenting cells to promote T(H)17 response and the development of pneumonitis and fibrosis following gammaherpesvirus infection

Hematopoietic stem cell transplantation (HSCT) efficacy is limited by numerous pulmonary complications. We developed a model of syngeneic bone marrow transplant (BMT) followed by infection with murine gamma herpesvirus (γHV-68) that results in pneumonitis and fibrosis and mimics human “non-infectiou...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaofeng, Loomis-King, Hillary, Gurczynski, Stephen J., Wilke, Carol A., Konopka, Kristine E., Ptaschinski, Catherine, Coomes, Stephanie M, Iwakura, Yoichiro, van Dyk, Linda F., Lukacs, Nicholas W., Moore, Bethany B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794430/
https://www.ncbi.nlm.nih.gov/pubmed/26376362
http://dx.doi.org/10.1038/mi.2015.85

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