The Toxicokinetic Profile of Dex40-GTMAC3—a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin

Though protamine sulfate is the only approved antidote of unfractionated heparin (UFH), yet may produce life threatening side effects such as systemic hypotension, catastrophic pulmonary vasoconstriction or allergic reactions. We have described 40 kDa dextrans (Dex40) substituted with glycidyltrimet...

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Detalles Bibliográficos
Autores principales: Sokolowska, Emilia, Kalaska, Bartlomiej, Kaminski, Kamil, Lewandowska, Alicja, Blazejczyk, Agnieszka, Wietrzyk, Joanna, Kasacka, Irena, Szczubialka, Krzysztof, Pawlak, Dariusz, Nowakowska, Maria, Mogielnicki, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794501/
https://www.ncbi.nlm.nih.gov/pubmed/27014072
http://dx.doi.org/10.3389/fphar.2016.00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794501/
https://www.ncbi.nlm.nih.gov/pubmed/27014072
http://dx.doi.org/10.3389/fphar.2016.00060

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