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Blood Lactate Is a Useful Indicator for the Medical Emergency Team

Lactate has been thoroughly studied and found useful for stratification of patients with sepsis, in the Intensive Care Unit, and trauma care. However, little is known about lactate as a risk-stratification marker in the Medical Emergency Team- (MET-) call setting. We aimed to determine whether the a...

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Autores principales: Schollin-Borg, Maria, Nordin, Pär, Zetterström, Henrik, Johansson, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794570/
https://www.ncbi.nlm.nih.gov/pubmed/27042345
http://dx.doi.org/10.1155/2016/5765202
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author Schollin-Borg, Maria
Nordin, Pär
Zetterström, Henrik
Johansson, Joakim
author_facet Schollin-Borg, Maria
Nordin, Pär
Zetterström, Henrik
Johansson, Joakim
author_sort Schollin-Borg, Maria
collection PubMed
description Lactate has been thoroughly studied and found useful for stratification of patients with sepsis, in the Intensive Care Unit, and trauma care. However, little is known about lactate as a risk-stratification marker in the Medical Emergency Team- (MET-) call setting. We aimed to determine whether the arterial blood lactate level at the time of a MET-call is associated with increased 30-day mortality. This is an observational study on a prospectively gathered cohort at a regional secondary referral hospital. All MET-calls during the two-year study period were eligible. Beside blood lactate, age and vital signs were registered at the call. Among the 211 calls included, there were 64 deaths (30.3%). Median lactate concentration at the time of the MET-call was 1.82 mmol/L (IQR 1.16–2.7). We found differences between survivors and nonsurvivors for lactate and oxygen saturation, a trend for age, but no significant correlations between mortality and systolic blood pressure, respiratory rate, and heart rate. As compared to normal lactate (<2.44 mmol/L), OR for 30-day mortality was 3.54 (p < 0.0006) for lactate 2.44–5.0 mmol/L and 4.45 (p < 0.0016) for lactate > 5.0 mmol/L. The present results support that immediate measurement of blood lactate in MET call patients is a useful tool in the judgment of illness severity.
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spelling pubmed-47945702016-04-03 Blood Lactate Is a Useful Indicator for the Medical Emergency Team Schollin-Borg, Maria Nordin, Pär Zetterström, Henrik Johansson, Joakim Crit Care Res Pract Research Article Lactate has been thoroughly studied and found useful for stratification of patients with sepsis, in the Intensive Care Unit, and trauma care. However, little is known about lactate as a risk-stratification marker in the Medical Emergency Team- (MET-) call setting. We aimed to determine whether the arterial blood lactate level at the time of a MET-call is associated with increased 30-day mortality. This is an observational study on a prospectively gathered cohort at a regional secondary referral hospital. All MET-calls during the two-year study period were eligible. Beside blood lactate, age and vital signs were registered at the call. Among the 211 calls included, there were 64 deaths (30.3%). Median lactate concentration at the time of the MET-call was 1.82 mmol/L (IQR 1.16–2.7). We found differences between survivors and nonsurvivors for lactate and oxygen saturation, a trend for age, but no significant correlations between mortality and systolic blood pressure, respiratory rate, and heart rate. As compared to normal lactate (<2.44 mmol/L), OR for 30-day mortality was 3.54 (p < 0.0006) for lactate 2.44–5.0 mmol/L and 4.45 (p < 0.0016) for lactate > 5.0 mmol/L. The present results support that immediate measurement of blood lactate in MET call patients is a useful tool in the judgment of illness severity. Hindawi Publishing Corporation 2016 2016-03-03 /pmc/articles/PMC4794570/ /pubmed/27042345 http://dx.doi.org/10.1155/2016/5765202 Text en Copyright © 2016 Maria Schollin-Borg et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Schollin-Borg, Maria
Nordin, Pär
Zetterström, Henrik
Johansson, Joakim
Blood Lactate Is a Useful Indicator for the Medical Emergency Team
title Blood Lactate Is a Useful Indicator for the Medical Emergency Team
title_full Blood Lactate Is a Useful Indicator for the Medical Emergency Team
title_fullStr Blood Lactate Is a Useful Indicator for the Medical Emergency Team
title_full_unstemmed Blood Lactate Is a Useful Indicator for the Medical Emergency Team
title_short Blood Lactate Is a Useful Indicator for the Medical Emergency Team
title_sort blood lactate is a useful indicator for the medical emergency team
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794570/
https://www.ncbi.nlm.nih.gov/pubmed/27042345
http://dx.doi.org/10.1155/2016/5765202
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