Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

The effects of abnormalities in the DNA glycosylases NEIL1, NEIL2, and NEIL3 on human cancer have not been fully elucidated. In this paper, we found that the median somatic total mutation loads and the median somatic single nucleotide mutation loads exhibited significant inverse correlations with th...

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Detalles Bibliográficos
Autores principales: Shinmura, Kazuya, Kato, Hisami, Kawanishi, Yuichi, Igarashi, Hisaki, Goto, Masanori, Tao, Hong, Inoue, Yusuke, Nakamura, Satoki, Misawa, Kiyoshi, Mineta, Hiroyuki, Sugimura, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794593/
https://www.ncbi.nlm.nih.gov/pubmed/27042257
http://dx.doi.org/10.1155/2016/1546392

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