Cargando…

Regulations of Reversal of Senescence by PKC Isozymes in Response to 12-O-Tetradecanoylphorbol-13-Acetate via Nuclear Translocation of pErk1/2

The mechanism by which 12-O-tetradecanoylphorbol-13-acetate (TPA) bypasses cellular senescence was investigated using human diploid fibroblast (HDF) cell replicative senescence as a model. Upon TPA treatment, protein kinase C (PKC) α and PKCβ1 exerted differential effects on the nuclear translocatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Yun Yeong, Ryu, Min Sook, Kim, Hong Seok, Suganuma, Masami, Song, Kye Yong, Lim, In Kyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794609/ https://www.ncbi.nlm.nih.gov/pubmed/26912086 http://dx.doi.org/10.14348/molcells.2016.2362

Ejemplares similares

12-O-Tetradecanoylphorbol-13-acetate increases cardiomyogenesis through PKC/ERK signaling
por: Radaszkiewicz, Katarzyna Anna, et al.
Publicado: (2020)

Depletion of protein kinase C (PKC) by 12- O -tetradecanoylphorbol-13-acetate (TPA) enhances platinum drug sensitivity in human ovarian carcinoma cells
por: Isonishi, S, et al.
Publicado: (2000)

Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines
por: Abou-Kandil, Ammar, et al.
Publicado: (2012)

Acetate Kinase Isozymes Confer Robustness in Acetate Metabolism
por: Chan, Siu Hung Joshua, et al.
Publicado: (2014)

12-O-tetradecanoylphorbol 13-acetate induced differentiation in human lung squamous carcinoma cells.
por: Rabiasz, G. J., et al.
Publicado: (1992)

12-O-tetradecanoylphorbol-13-acetate Reduces Activation of Hepatic Stellate Cells by Inhibiting the Hippo Pathway Transcriptional Coactivator YAP
por: Kim, Chang Wan, et al.
Publicado: (2022)

Regulation of Transcriptional Networks by PKC Isozymes: Identification of c-Rel as a Key Transcription Factor for PKC-Regulated Genes
por: Garg, Rachana, et al.
Publicado: (2013)

Opposed Actions of PKA Isozymes (RI and RII) and PKC Isoforms (cPKCβI and nPKCε) in Neuromuscular Developmental Synapse Elimination
por: Garcia, Neus, et al.
Publicado: (2019)

Cytosolic‐nuclear Tumor Promoter‐specific Binding Protein: Association with the 90 kDa Heat Shock Protein and Translocation into Nuclei by Treatment with 12‐O‐Tetradecanoylphorbol 13‐Acetate
por: Hashimoto, Yuichi, et al.
Publicado: (1991)

Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways
por: Lii, Chong-Kuei, et al.
Publicado: (2016)

Protein Kinase C (PKC) Isozymes as Diagnostic and Prognostic Biomarkers and Therapeutic Targets for Cancer
por: Kawano, Takahito, et al.
Publicado: (2022)

Effects of chronic topical application of 12-O-tetradecanoylphorbol-13-acetate on the skin and internal organs of SENCAR mice.
por: Klein-Szanto, A J, et al.
Publicado: (1986)

12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2
por: Lee, Eun Ji, et al.
Publicado: (2014)

Anti-inflammatory effect of aged black garlic on 12-O-tetradecanoylphorbol-13-acetate-induced dermatitis in mice
por: You, Bo Ram, et al.
Publicado: (2019)

Diverse dynamics features of novel protein kinase C (PKC) isozymes determine the selectivity of a fluorinated balanol analogue for PKCε
por: Hardianto, Ari, et al.
Publicado: (2019)

Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
por: Cho, Jiyoon, et al.
Publicado: (2015)

The expression of protein kinase B in gastric cancer cell apoptosis induced by 12-O-tetradecanoylphorbol-1, 3-acetate
por: Zhang, Bing, et al.
Publicado: (2009)

PKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysema.
por: Avelar, Erick, et al.
Publicado: (2005)

Effect of 12-O-tetradecanoylphorbol-13-acetate on two charateristics of transformation acquired sequentially by ENU-exposed rat brain cells.
por: Roscoe, J. P., et al.
Publicado: (1980)

The tumour promoter 12-O-tetradecanoylphorbol-13-acetate increases the activities of some peroxisome-associated enzymes in in vitro cell culture.
por: Lillehaug, J. R., et al.
Publicado: (1986)

Suppression of Transglutaminase-2 is Involved in Anti-Inflammatory Actions of Glucosamine in 12-O-Tetradecanoylphorbol-13-Acetate-Induced Skin Inflammation
por: Park, Mi Kyung, et al.
Publicado: (2012)

12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT
por: Zhu, Guoqing, et al.
Publicado: (2017)

12-O-tetradecanoylphorbol-13-acetate (TPA) increases murine intestinal crypt stem cell survival following radiation injury
por: Liang, Yaojie, et al.
Publicado: (2017)

An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins
por: Gada, Kirin D., et al.
Publicado: (2022)

Auricular Electroacupuncture Reduced Inflammation-Related Epilepsy Accompanied by Altered TRPA1, pPKCα, pPKCε, and pERk1/2 Signaling Pathways in Kainic Acid-Treated Rats
por: Lin, Yi-Wen, et al.
Publicado: (2014)

No Involvement of Lysophosphatidic Acid Receptor-3 in Cell Migration of Mouse Lung Tumor Cells Stimulatedby 12-O-Tetradecanoylphorbol-13-acetate
por: Okumura, Mai, et al.
Publicado: (2011)

Anti-inflammatory effect of aqueous extracts of spent Pleurotus ostreatus substrates in mouse ears treated with 12-O-tetradecanoylphorbol-13-acetate
por: Rivero-Pérez, Nallely, et al.
Publicado: (2016)

Cell Signaling Pathway in 12-O-Tetradecanoylphorbol-13-acetate-Induced LCN2 Gene Transcription in Esophageal Squamous Cell Carcinoma
por: Meng, Lingying, et al.
Publicado: (2017)

Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21(WAF1)-PKCζ pathway in p16(INK4a)-silenced cells
por: Lee, Yun Yeong, et al.
Publicado: (2020)

ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics
por: Levidou, Georgia, et al.
Publicado: (2012)

Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin
por: Wei, Wen-Chi, et al.
Publicado: (2011)

Combination of 12-O-tetradecanoylphorbol-13-acetate with diethyldithiocarbamate markedly inhibits pancreatic cancer cell growth in 3D culture and in immunodeficient mice
por: HUANG, HUARONG, et al.
Publicado: (2015)

Anti‐inflammatory effect of lanoconazole on 12‐O‐tetradecanoylphorbol‐13‐acetate‐ and 2,4,6‐trinitrophenyl chloride–induced skin inflammation in mice
por: Nakamura, Aki, et al.
Publicado: (2019)

Protein kinase C in the wood frog, Rana sylvatica: reassessing the tissue-specific regulation of PKC isozymes during freezing
por: Dieni, Christopher A., et al.
Publicado: (2014)

Crotonis Fructus Extract Inhibits 12-O-Tetradecanoylphorbol-13-Acetate-Induced Expression of Matrix Metalloproteinase-9 via the Activator Protein-1 Pathway in MCF-7 Cells
por: Song, Hyun-Kyung, et al.
Publicado: (2017)

Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice
por: Madsen, Marie, et al.
Publicado: (2016)

Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4(+) T Lymphocytes
por: Tsai, Cheng-Chieh, et al.
Publicado: (2020)

A NANOG‐pERK reciprocal regulatory circuit regulates Nanog autoregulation and ERK signaling dynamics
por: Kale, Hanuman T, et al.
Publicado: (2022)

Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells
por: Perveen, Khalida, et al.
Publicado: (2019)

PKCα diffusion and translocation are independent of an intact cytoskeleton
por: Hui, Xin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sd1p9hjgfilnjqkp8d3ruqn6jv